For the stuff that remains, I am a firm believer in using baskets to corral like items, pocket file folders or rolling files for paper projects, and multi-purpose furniture that can be closed up when not in use. That way, you can designate between "work" time and "play" time. Simply remove from sight whatever is not being used in the moment.
Remember what our grandparents used to say: a place for everything and everything in its place. Having clear surfaces brings peace and tranquility to your space. Happy decluttering!